Natural Fiber Welding (NFW) is a process where ionic liquids are used to fabricate higher-order, functional biocomposites from biopolymer materials.  In this study, we evaluate for the first time how NFW can be applied to weld keratin-based wool fibers.  Starting with an industrially-cleaned fleece from a Valais sheep, we first use chemical processes (i.e, soxhlet extraction, base treatment) to remove internal lipids from the fiber surface.  Then a series of NFW experiments are performed, systematically exploring the effectiveness of four welding solvents with and without sodium sulfite.  Each step of the process is evaluated using scanning electron microscopy, infrared spectroscopy, and thermal gravimetric analysis.