The constraint-release hypothesis is a critical hypothesis in the field of evolution, which states that there are constraints on certain adaptations that can be released by other adaptations or by environmental change. In this study, we test the constraint-release hypothesis by looking at snake vertebrae. Snakes that rely on constriction to catch prey are limited to having a certain number range of vertebrae that is ideal for constriction. When a snake uses venom, there is a lower evolutionary pressure to maintain a certain number of vertebrae. Thus, the restriction on vertebrae counts would be released in venomous snakes, giving them higher variability in vertebrae counts. By investigating the number of vertebrae in constricting and non-constricting snakes, we hoped to find evidence supporting or not supporting this hypothesis. Our hypothesis based on the constraint-release hypothesis states that there will be more variation in the number of vertebrae of venomous snakes than constricting snakes. To investigate this, we conducted a literature review to find the vertebrae counts of a representative species for all snake families. We calculated the standard deviation among vertebrae counts in individuals of each species. Then we separated the data into two groups: constricting and non-constricting snakes. We then ran an ANOVA analysis comparing the standard deviations of each species in each of the two groups. It was found that non-constricting snake species did not have lower standard deviations in vertebrae count than constricting snake species.